Nur77 deficiency leads to systemic inflammation in elderly mice

nuri77Fure 1 Loss of Nur77 in BMDMs leads to enhanced efferocytosis due to an increased integrin β3 and β5 snaling.(A) In vitro uptake of fluorescently-labeled apoptoticArticle The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome Fangrui Zhu,1,2,3,8 Juan Ma,1,2,3,8 Weitao Li,1,2,3,8 Qiannv Liu,1,2,3,8